dr Dean A Sewell

Dr Dean A Sewell

Senior Lecturer

Dean Sewell joined Heriot-Watt University in 2001, having previously worked at the University of Warwick, University of Nottingham Medical School and an industrially sponsored nutrition research unit based in Maastricht University in the Netherlands. In 2002 he ran the Everest marathon and has completed the Yorkshire Dales Three Peaks fell race on numerous occasions.  He was Director of Sport and Exercise Science in the School (2001-2007), has been School Undergraduate Recruitment and Admissions tutor, and is an elected member of the University Senate. His research interests are centred on muscle and exercise metabolism and nutrient interactions.   

  

Selected References

Sewell, D.A., Robinson, T.M., Greenhaff, P.L. (2008). Creatine supplementation does not affect muscle glycogen accumulation in non-exercising human muscle. J. App. Physiol. 104, 508-512.

Sewell, D.A., McGregor, R.A. (2008). Evaluation of a cycling pre-load time trial protocol in recreationally active humans. Eur. J. App. Physiol. 102, 615-621.

Keller P, Vollaard NBJ, Babraj J, Ball D, Sewell DA, Timmons JA (2007). Using systems biology to define the essential biological networks responsible for adaptation to endurance exercise training. Biochem.Soc.Trans., 35 (5), 1306-9. Link

Schéele C, Nielsen AR, Walden TB, Sewell DA, Fischer CP, Brogan RJ, Petrovic N, Larsson O, Tesch P, Wennmalm K, Hutchinson D, Cannon B, Wahlestedt C, Pedersen BK and Timmons JA. Altered regulation of the PINK1 locus: a link between type 2 diabetes and neurodegeneration? FASEB, doi: 10.1096/fj.07-8520com, 2007. Link

Sewell, DA. (2005) Anatomy and Physiology. In: Sewell DA, Watkins P, Griffin, M.: Sport and Exercise Science – An introduction. Hodder Arnold. ISBN: 0 340 81569 8

Robinson TM, Sewell DA, Greenhaff PL (2003). A tolerable amount of oral L-Arginine does not affect glucose disposal in rested or exercised humans. Med. Sci. Sports Exerc., 35, 1309-1315.

Robinson, T.M., Sewell, D.A., Casey, A., Steenge, G., Greenhaff, P.L. (2000). Dietary creatine supplementation does not effect some haematological indices, or indices of muscle damage and hepatic and renal function. Br. J. Sports Med. 34, 284-288. Link

Green, A.L., Hultman, E., Macdonald, I.A., Sewell, D.A., Greenhaff, P.L. (1996). Carbohydrate ingestion augments skeletal muscle creatine accumulation during creatine supplementation in humans. Am. J. Physiol. 271 (Endocrinol. Metab. 34): E821 - E826.

Gleeson, M., Blannin A.K., Sewell, D.A., Cave R. (1995). Short-term changes in the blood leucocyte and platelet count following different durations of high intensity treadmill running. J. Sports Sci. 13, 115-123

Sewell D.A., Harris R.C. (1995). Effects of creatine supplementation in the thoroughbred horse. Equine Vet. J., Suppl. 18, 239-242.

Sewell D.A., Harris R.C., Marlin, D.J. (1994). Skeletal muscle characteristics in 2 year-old race-trained thoroughbred horses. Comp. Biochem. Physiol. 108A, 87-96. Link

Sewell D.A., Gleeson, M., Blannin A. (1994). Hyperammonaemia in relation to high intensity exercise duration in man. Eur. J. Appl. Physiol. Occup. Physiol. 69, 350-354 Link

Sewell D.A., Harris R.C., Hanak J., Jahn P. (1992). Muscle adenine nucleotide degradation in the thoroughbred horse as a consequence of racing. Comp. Biochem. Physiol. 101B, 375-381. Link

Sewell D.A., Harris R.C., Marlin D.J., Dunnett M. (1992). Estimation of the carnosine content of different fibre types in the middle gluteal muscle of the thoroughbred horse. J. Physiol.(Lond). 455, 447-453.

Sewell D.A., Harris R.C. (1992). Adenine nucleotide degradation in the thoroughbred horse with increasing exercise duration. Eur. J. Appl. Physiol. Occup. Physiol. 65, 271-277.

Dunnett M., Harris R.C., Sewell D.A. (1992). Taurine content and distribution in equine skeletal muscle. Scand. J. Clin. Lab. Invest. 52, 725-730.

Sewell D.A., Harris R.C., Dunnett M. (1991). Carnosine accounts for most of the variation in physico-chemical buffering in equine muscle. In: Persson S.G.B., Lindholm A., Jeffcott L.B. (eds): Equine Exercise Physiology 3, ICEEP Publications, Davis, CA, pp 276-280

Greenhaff P.L., Harris R.C., Snow D.H., Sewell D.A., Dunnett M. (1991). The influence of metabolic alkalosis upon exercise metabolism in the thoroughbred horse. Eur. J. Appl. Physiol. Occup. Physiol. 63, 129-134.

Stocks R.J., Davies D.P., Allen F., Sewell D. (1985). Loss of breast milk nutrients during tube feeding. Arch. Dis. Childhood. 60, 164-166.

 

Further Information is available here.  

  

Contact Details

Dr Dean A. Sewell

School of Life Sciences
Heriot-Watt University
Riccarton
Edinburgh EH14 4AS
U.K.

Direct Telephone: +44(0) 131 451 8178
Fax:                    +44(0) 131 451 3009
E-mail: D.A.Sewell@hw.ac.uk

 

Published Papers Available as Download

 

 

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